Creatinine-Based Estimated Glomerular Filtration Rate (eGFR) — 2021 CKD-EPI Equation, Calculated
A calculated estimate of kidney filtering function based on creatinine, age, and sex, using the 2021 CKD-EPI equation.
["This blood-based calculation helps assess how well the kidneys filter waste."]
Key facts at a glance
- LOINC
- 55767-8
- Short code
- EGFR c.2582T>A Bld/T Ql
- Synonyms
- EGFR c.2582T>A Bld/T Ql
- Category
- kidney
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 90
- Ref high
- 120
- Critical range
- 15 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- CPT
- 82565
- SNOMED
- 247997009
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
Estimated glomerular filtration rate, or eGFR, estimates how much blood the kidneys filter each minute. It is calculated using a creatinine measurement together with age and sex, using the 2021 CKD-EPI equation, which does not use race as a factor.
Why might I need this test?
eGFR is commonly used to screen for and monitor reduced kidney function, including chronic kidney disease. It may also help guide medication dosing, fluid management, and follow-up for people with diabetes, high blood pressure, or other kidney-related conditions.
How is the test performed?
A blood sample is usually used to measure serum or plasma creatinine. The laboratory combines that result with the patient's age and sex to calculate eGFR, which is commonly reported in milliliters per minute per 1.73 square meters.
How do I prepare for the test?
A creatinine blood test generally does not require fasting, but instructions may vary if the eGFR is being ordered with other tests. Tell the healthcare provider about recent illness, pregnancy, unusual changes in muscle mass, and medications or supplements that may affect creatinine.
Reference range
Normal: >90 mL/min/1.73m²N/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A low eGFR may indicate reduced kidney filtration, but one result alone does not establish chronic kidney disease; persistent abnormality and other findings are needed. An unexpectedly high value can occur with pregnancy, recent exercise, high muscle mass, or a high-protein diet. Results should be interpreted alongside creatinine, urine findings, medical history, and trends over time.
Short name
eGFR (2021 CKD-EPI, Creatinine-Based)
Frequently asked questions
Is eGFR a blood test?
Does a low eGFR mean I have kidney disease?
What can affect my eGFR?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy