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Serum/plasma mass concentration of erythropoietin (EPO)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of erythropoietin (EPO), a hormone produced mainly in the kidneys, that helps your body make red blood cells. It may be checked to evaluate kidney function, anemia, or responses to treatments like erythropoiesis-stimulating agents.

Quick summary

["EPO levels help assess kidney health and red blood cell production."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14049-1
Short code
EGF SerPl-mCnc
Synonyms
EGF SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms of anemia (such as fatigue, weakness, or shortness of breath), unexplained low red blood cell counts, or if you’re being treated for conditions like chronic kidney disease. It can also be used to monitor how your body responds to medications that stimulate red blood cell production.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re having a urine test, you might need to collect a sample over a 24-hour period, depending on the reason for the test.

What Happens During the Test?

For blood tests, a healthcare professional will insert a small needle into a vein in your arm. A small amount of blood will be drawn and sent to a lab for analysis. If a urine sample is involved, you’ll collect it in a container at home or in a clinic.

What Do Results Mean?

Results are interpreted based on your medical history, symptoms, and other lab tests. Abnormal levels may indicate conditions like kidney disease, anemia, or certain cancers. Your doctor will discuss the results with you in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: EPO Levels

Short name

EPO Level

Frequently asked questions

How often should I get this test?
The frequency depends on your medical condition. If you have kidney disease, your doctor may recommend regular monitoring. If you’re taking EPO-based treatments, tests might be done more often to check for side effects or effectiveness.
What are the normal ranges for EPO?
There are no standard reference ranges provided here since they vary by lab and individual health. Your doctor will use your specific results in relation to your symptoms and other tests to guide diagnosis and treatment.
Can I eat or drink before this test?
For blood tests, fasting may be required for 8–12 hours before drawing blood. For urine tests, follow your doctor’s instructions, as some may require a 24-hour urine collection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy