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Serum or Plasma Electrophoresis (Protein Electrophoresis)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, helping identify abnormalities in protein distribution that may signal conditions like multiple myeloma, liver disease, or other disorders.

Quick summary

["This test helps doctors check for unusual protein patterns that could indicate health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7296-7
Short code
Eggplant IgE Qn
Synonyms
Eggplant IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a protein electrophoresis test to investigate symptoms such as unexplained weight loss, fatigue, bone pain, or changes in kidney function. It’s also used to monitor conditions like multiple myeloma, amyloidosis, or chronic liver disease.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if blood is drawn. Wear comfortable clothing and plan for a short visit to the lab. A healthcare provider will draw blood from a vein in your arm.

What Happens During the Test

Blood is collected in a tube and sent to a lab. The sample is then separated into different protein fractions using an electric field, creating distinct bands on a gel. These bands are analyzed to identify protein patterns.

Possible Results and Next Steps

Abnormal patterns (e.g., spikes in certain protein bands) may require further testing, such as bone marrow biopsy or additional bloodwork, to diagnose conditions like multiple myeloma or kidney disease. Your doctor will discuss results with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis

Frequently asked questions

What does an abnormal result mean?
Abnormal results may indicate conditions affecting protein production, such as multiple myeloma (a cancer of plasma cells), kidney disease, liver disease, or certain autoimmune disorders. A doctor will interpret results in the context of your symptoms and medical history.
Can I eat or drink before the test?
If blood is drawn, avoid food for 8–12 hours before the test. Water is usually allowed unless otherwise instructed by your doctor.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will explain the findings during a follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy