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Albumin in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of albumin, a key protein in your blood, which helps maintain fluid balance and supports the immune system.

Quick summary

["Albumin levels can indicate overall health and help diagnose conditions like kidney disease or malnutrition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56253-8
Short code
Egg White IgG4-mCnc
Synonyms
Egg White IgG4-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Albumin Does in Your Body

Albumin is one of the most abundant proteins in your blood. It plays a critical role in transporting nutrients, hormones, and medications, as well as helping maintain proper fluid balance between your blood vessels and tissues. Low albumin levels may suggest problems like liver disease, kidney issues, or severe infections.

Why It’s Tested

Doctors may order albumin tests to check for conditions affecting protein production, fluid balance, or kidney function. It’s often part of a broader evaluation for chronic illnesses like heart failure, cirrhosis, or malnutrition.

What Normal Results Mean

While specific reference ranges vary by lab, healthy albumin levels typically reflect adequate protein synthesis and kidney function. Abnormally low or high levels may signal underlying health concerns that need further investigation.

Common Conditions Linked to Albumin Levels

Low albumin is often seen in conditions like cirrhosis (liver disease), kidney failure, or severe infections. High levels may occur in dehydration or certain inflammatory states, though this is less common.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Albumin levels help assess nutritional status, liver and kidney health, and fluid balance. They’re also used to monitor treatment responses in chronic diseases.

Short name

Albumin Level

Frequently asked questions

What causes low albumin levels?
Low albumin can result from liver disease (reducing protein production), kidney problems (losing protein in urine), malnutrition, chronic infections, or excessive protein loss (e.g., from burns or severe diarrhea).
How do I prepare for this test?
No special preparation is needed. You may drink water as usual, but avoid alcohol for 24 hours before testing if advised by your doctor.
Can high albumin levels be dangerous?
Rarely, very high albumin levels may indicate dehydration or certain inflammatory conditions. However, most cases are benign and related to normal fluid shifts. Always discuss results with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy