Albumin to Globulin Ratio (A/G Ratio) - Serum

What Does This Test Measure?

Albumin and globulin are types of proteins found in your blood. Albumin helps maintain fluid balance in your body, while globulins play roles in immune function and transport of substances like hormones and metals. The A/G ratio compares their amounts, which can reflect overall protein status and health of organs like the liver.

Why Might You Need This Test?

Doctors may order an A/G ratio test to evaluate conditions such as malnutrition, liver disease, chronic kidney disease, or certain immune disorders. It can also help monitor treatment responses in patients with protein-related conditions.

How Is This Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The serum portion is separated and analyzed to determine the protein levels of albumin and globulin, then their ratio is calculated.

What Are Common Causes of Abnormal Results?

Low A/G ratio may suggest malnutrition, liver disease, or chronic kidney disease. A high ratio could indicate conditions like multiple myeloma (a blood cancer), severe liver disease, or dehydration. Results alone don’t diagnose specific conditions but may prompt further testing.