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Serum Immunoglobulin G (IgG) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections by fighting bacteria and viruses.

Quick summary

["IgG levels help assess immune function and identify potential immune deficiencies or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51536-1
Short code
Egg White IgG Ql
Synonyms
Egg White IgG Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgG Measure?

IgG is the most abundant antibody in your blood and plays a critical role in long-term immunity. It’s produced by your immune system to defend against a wide range of pathogens, including bacteria and viruses. Measuring IgG helps doctors evaluate how well your immune system is working, especially in people with weakened immunity due to conditions like HIV, cancer treatments, or certain genetic disorders.

Why Might You Need This Test?

Your doctor may order an IgG test if you have symptoms like frequent infections, slow wound healing, or if you’re receiving treatments that suppress your immune system. It can also be used to monitor immune responses in people with autoimmune diseases or those receiving immune-boosting therapies.

Common Reasons for Testing

IgG testing is often done to diagnose or monitor conditions such as immunodeficiency diseases, infections (like tuberculosis or HIV), or to check immune responses before or after vaccination. It may also be part of a broader evaluation for chronic diseases like lupus or rheumatoid arthritis.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample, which usually takes a few minutes. If you’re on blood thinners or have a history of bleeding, let your doctor know beforehand.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

How IgG Levels Can Affect Your Health

Short name

IgG Level

Frequently asked questions

How long does it take to get IgG test results?
IgG test results are typically available within 1 to 3 business days, depending on your lab. Your doctor will discuss the results with you during your follow-up visit.
What do low IgG levels mean?
Low IgG levels may indicate an immune deficiency, where your body struggles to fight infections effectively. This could be due to genetic disorders, certain medications, or conditions like HIV or cancer treatments. Your doctor will work with you to determine the best next steps, which may include additional tests or treatments.
Can IgG levels change over time?
Yes, IgG levels can fluctuate for several reasons, including infections, vaccinations, aging, or underlying health conditions. Regular monitoring may be needed if you have a chronic illness or are receiving treatments that affect your immune system.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy