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Lipoprotein(a) mass concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of lipoprotein(a) in your blood, a type of cholesterol-related protein that may increase your risk of heart disease.

Quick summary

["Lipoprotein(a) is linked to higher cardiovascular risks; knowing your levels helps assess your risk for heart attacks or strokes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56254-6
Short code
Egg Yolk IgG4-mCnc
Synonyms
Egg Yolk IgG4-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is lipoprotein(a)?

Lipoprotein(a) is a unique lipoprotein particle that combines cholesterol with a protein called apolipoprotein(a). While it carries cholesterol like other lipoproteins, it also has a distinct role in blood clotting. Elevated levels may contribute to plaque buildup in arteries, increasing the risk of heart disease or stroke.

Why might your doctor order this test?

Your doctor may recommend this test if you have a family history of early heart disease, certain genetic conditions, or if you’ve had a heart attack or stroke. It may also be part of a broader cardiovascular risk assessment, especially if you have high cholesterol or other risk factors.

How is the test performed?

A blood sample is drawn from a vein, typically in your arm. The sample is processed to separate the lipoprotein(a) from other blood components, and the amount is measured using a specialized laboratory technique.

What does a high or low result mean?

Results are not interpreted in absolute terms without clinical context. High levels of lipoprotein(a) are associated with increased cardiovascular risk, while low levels may indicate a lower risk. Your doctor will consider your overall health, other risk factors, and test results together to guide treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

How does lipoprotein(a) relate to heart health?

Short name

Lp(a) mass concentration

Frequently asked questions

What causes lipoprotein(a) levels to change?
Lipoprotein(a) levels are generally stable over time, but they can be influenced by genetics, certain medications (like statins), and conditions like high blood pressure or diabetes. Lifestyle factors, such as diet and exercise, may also play a subtle role.
Can lifestyle changes lower lipoprotein(a) levels?
While lifestyle changes like eating heart-healthy foods, managing weight, and quitting smoking can improve overall cardiovascular health, there is no strong evidence that they significantly lower lipoprotein(a) levels on their own. Genetic factors play a major role in determining your baseline level.
How often should I get this test?
Your doctor will determine how often you need this test based on your individual risk profile. If you have a high risk, it may be part of routine cardiovascular screening, possibly every few years or as recommended by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy