Cerebrospinal Fluid White Blood Cell Count (Qualitative)
This test checks the number of white blood cells in your cerebrospinal fluid (CSF), which is the fluid surrounding your brain and spinal cord. It helps identify infections, inflammation, or other conditions affecting the central nervous system.
["A CSF white blood cell count helps diagnose potential infections or immune responses in your brain or spinal cord."]
Key facts at a glance
- LOINC
- 47406-4
- Short code
- E histolyt Ab CSF Ql
- Synonyms
- E histolyt Ab CSF Ql
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
White blood cells in the CSF are normally very low or absent. Elevated counts can signal conditions like meningitis, encephalitis, or other inflammatory processes. The test is often performed alongside other CSF tests (such as protein or glucose levels) for a full assessment.
How the Test Works
A small sample of CSF is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then examined under a microscope to count white blood cells. This is a qualitative test, meaning it provides a yes/no or low/high indication rather than a precise number.
When You Might Need This Test
Your doctor may order this test if you have symptoms like severe headache, neck stiffness, fever, confusion, or neurological symptoms (e.g., numbness, weakness). It’s also used to monitor conditions like multiple sclerosis or other central nervous system diseases.
What to Expect Before the Test
You’ll likely receive a local anesthetic to numb the area where the needle will be inserted. You may need to lie still for a short time afterward. Avoid heavy lifting or strenuous activity for 24 hours to prevent complications.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF WBC Qual
Frequently asked questions
What does an elevated white blood cell count in CSF mean?
What if my test results are abnormal?
Does this test require fasting?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy