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Eosinophil count in serum/plasma (qualitative or semi-quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test helps assess the presence of eosinophils, a type of white blood cell, in your blood. Eosinophils are involved in allergic reactions and certain infections.

Quick summary

["Eosinophils may rise in allergic conditions, parasitic infections, or other immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22285-1
Short code
E histolyt Ab Ser Ql
Synonyms
E histolyt Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

When might this test be needed?

Your doctor may order this test if you have symptoms like persistent itching, skin rashes, asthma, or unexplained allergies. It could also be used to monitor conditions like eosinophilic esophagitis, certain infections, or reactions to medications.

What does an abnormal result mean?

A higher-than-normal eosinophil count may indicate allergies, parasitic infections, certain autoimmune diseases, or reactions to drugs. A lower-than-normal count might suggest immune suppression or other underlying health issues.

How is this test performed?

A blood sample is drawn from a vein, typically in your arm. The sample is then analyzed in a lab to detect and count eosinophils. The test may be qualitative (yes/no) or semi-quantitative (approximate levels).

What can affect this test?

Recent infections, allergies, certain medications (like steroids), or stress can temporarily change eosinophil levels. Avoiding recent infections or allergens for a few days before testing may help get more accurate results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Eosinophils play a key role in fighting parasites and responding to allergies. Elevated levels often point to allergic conditions, parasitic infections, or other inflammatory processes. Monitoring eosinophil counts can help guide treatment for conditions like asthma, eosinophilic gastrointestinal diseases, or certain drug reactions.

Short name

Eosinophil qualitative screening

Frequently asked questions

Why would my doctor order this test?
Your doctor may recommend this test to investigate symptoms like persistent itching, skin rashes, or unexplained allergic reactions. It can also help diagnose or monitor conditions like eosinophilic esophagitis, parasitic infections, or other eosinophil-related disorders.
What are the typical reference ranges?
Reference ranges for eosinophil counts vary by lab and may include qualitative (positive/negative) or approximate percentage ranges. Exact values are not provided here due to variability.
Is this test painful?
The blood draw itself may cause mild discomfort, but the test itself is not painful. Most people tolerate it well, and any minor discomfort fades quickly after the needle is removed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy