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Eosinophil count in serum/plasma (absolute)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of eosinophils, a type of white blood cell, in your blood serum or plasma. Eosinophils help fight infections caused by parasites and play a role in allergic reactions and certain inflammatory conditions.

Quick summary

["Eosinophils help protect your body from infections and allergies, and their levels can signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6397-4
Short code
E histolyt Ag Ser IA-aCnc
Synonyms
E histolyt Ag Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Done?

Your healthcare provider may order this test to evaluate symptoms such as persistent itching, skin rashes, asthma, or chronic sinusitis. It can also help diagnose conditions like allergies, parasitic infections, certain cancers (e.g., leukemia), or autoimmune disorders. Sometimes, elevated eosinophil counts are checked alongside other blood tests to identify the root cause of unexplained symptoms.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm to draw blood. If you’re concerned about pain or discomfort, let your provider know. If you’re on blood-thinning medications, inform your healthcare team beforehand.

What the Test Results Mean

Eosinophil counts are typically reported as a number of cells per microliter (cells/µL). While reference ranges vary by lab, elevated levels (above normal) may indicate allergies, infections, or inflammatory conditions. Very low levels might suggest immune system issues or certain blood disorders. Always discuss your results with your doctor.

Common Conditions Linked to Eosinophil Levels

High eosinophil counts can be linked to conditions like asthma, eosinophilic esophagitis, certain types of leukemia, parasitic infections, or allergic reactions. Low levels may be associated with immune deficiencies or other blood disorders. Your provider will consider your full medical history and symptoms to interpret results accurately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Eosinophil count

Frequently asked questions

What causes my eosinophil count to be high?
Elevated eosinophil counts can result from allergies, parasitic infections, certain cancers (like chronic eosinophilic leukemia), or inflammatory conditions such as asthma or eosinophilic gastrointestinal diseases. Stress, certain medications, or recent infections may also temporarily raise levels. If you notice persistent symptoms, talk to your doctor about further evaluation.
Can I lower my eosinophil count naturally?
While you can’t directly control eosinophil levels through diet alone, managing known triggers—like allergens, infections, or stress—may help. Avoiding known irritants (e.g., certain foods or environmental allergens), staying hydrated, and following your treatment plan (if prescribed) can support overall blood health. Always consult your provider before making changes.
How often should I get this test?
The frequency depends on your symptoms, medical history, and treatment plan. Your doctor may recommend this test periodically if you have conditions like asthma, allergies, or a history of eosinophilic disorders. Regular monitoring helps track your health and adjust care as needed. Follow your provider’s guidance for scheduling.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy