Skip to content

Cytogenetic analysis of peripheral blood DNA using a fluorescent in situ hybridization (FISH) probe for specific chromosomal abnormalities

Published: August 9, 2026Updated: August 16, 2026

This test examines your blood cells for genetic changes that may affect how your body functions, often used to detect conditions like certain cancers or genetic disorders.

Quick summary

["It helps identify hidden genetic issues that could influence your health or treatment options."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91766-6
Short code
E histolyt DNA Aspirate Ql NAA+probe
Synonyms
E histolyt DNA Aspirate Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of a genetic disorder, a family history of certain cancers, or if you’re at higher risk due to age or other factors. It can also be used to monitor known genetic conditions or check for abnormalities after treatments like chemotherapy.

What to Expect Before the Test

You’ll typically have a simple blood draw, similar to a regular blood test. No special preparation is needed, but inform your doctor about any medications or conditions that could affect results.

During the Test Process

Blood is collected in a tube, processed to isolate white blood cells, and then analyzed under a microscope using a fluorescent probe to detect specific genetic markers.

Possible Results and Next Steps

Results may show normal genetic material, or they could reveal abnormalities that require further testing or medical evaluation. Your doctor will discuss findings and next steps with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in diagnosing, monitoring, or guiding treatment for genetic disorders, certain cancers (like lymphoma or leukemia), or other conditions where chromosomal changes are suspected. It helps tailor treatments to your specific genetic profile.

Short name

Peripheral Blood FISH Probe Analysis

Frequently asked questions

Will this test hurt?
You might feel a slight pinch during the blood draw, but it’s usually over quickly. Most people don’t experience discomfort afterward.
How long will I need to wait for results?
Results can take several days to a couple of weeks, depending on lab processing and analysis. Your doctor will contact you once they’re ready.
Could this test affect my insurance or treatment options?
This test is typically covered by insurance if medically necessary. Your doctor will discuss how results may influence your care plan with you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy