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Eosinophil count in serum/plasma (qualitative or semiquantitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks the presence or level of eosinophils, a type of white blood cell, in your blood. Eosinophils help fight infections and respond to allergies or inflammatory conditions.

Quick summary

["Eosinophils can signal allergic reactions, infections, or other immune responses—your doctor may order this test for symptoms like itching, rashes, or unexplained fatigue."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22289-3
Short code
E histolyt IgM Ser-aCnc
Synonyms
E histolyt IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to diagnose or monitor conditions like allergies, asthma, parasitic infections, certain cancers (e.g., leukemia), or autoimmune diseases. It can also help evaluate symptoms like persistent itching, skin rashes, or digestive issues that don’t improve with other treatments.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a simple blood draw, usually at a doctor’s office or lab. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are qualitative (present/absent) or semiquantitative (approximate levels). High eosinophil counts may indicate allergies, infections, or inflammatory diseases, while very low counts could signal immune suppression or other health concerns. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions Linked to Eosinophil Levels

Elevated eosinophils are often seen in allergic reactions, parasitic infections, asthma, or certain cancers. Low levels may suggest conditions like HIV, certain autoimmune diseases, or prolonged stress on the immune system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Eosinophils play a key role in defending against parasites and regulating immune responses. They release chemicals that can cause inflammation or allergic symptoms. High levels may indicate an overactive immune response, while low levels could signal weakened immune function or hidden infections. Your doctor will use these results alongside other tests to guide treatment.

Short name

Eosinophil Screen/Confirm

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab. If you have urgent symptoms, ask your provider about follow-up timelines.
Can I eat or drink before this test?
No special diet is needed. You can eat and drink normally unless your doctor specifies otherwise. Avoid alcohol before blood tests if it may affect your blood count.
Is there any risk or discomfort with this test?
The blood draw is quick and usually painless. You might feel a slight pinch, but most people tolerate it well. Rarely, there could be mild bruising or swelling at the site. If you’re nervous, ask about numbing cream or other options.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy