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Eicosanoic Acid (C20:1) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the concentration of eicosanoic acid, a long-chain fatty acid found in your blood. Eicosanoids (derived from fatty acids like eicosanoic acid) play roles in inflammation, blood clotting, and other bodily functions.

Quick summary

["Understanding your eicosanoic acid levels may help assess metabolic or inflammatory health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53461-0
Short code
Eicosanoylcarn Amn-sCnc
Synonyms
Eicosanoylcarn Amn-sCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What Is Eicosanoic Acid?

Eicosanoic acid is a monounsaturated fatty acid with 20 carbon atoms. While it’s not as well-known as shorter-chain fatty acids (like omega-3 or omega-6), it can be a marker in certain metabolic or biochemical studies, especially when combined with other fatty acids or their derivatives (e.g., eicosanoids). Your doctor may order this test to investigate metabolic disorders, lipid metabolism, or as part of a broader fatty acid profile.

Why Might This Test Be Ordered?

This test may be requested if you have symptoms or conditions related to abnormal fatty acid metabolism, such as rare lipid disorders, metabolic syndrome, or when evaluating specific biochemical pathways. It could also be part of a research study or specialized diagnostic panel.

Sample Collection and Preparation

Blood is typically collected in a tube that separates serum (liquid part after clotting) or plasma (liquid part after centrifugation). The sample is sent to a lab for analysis using advanced techniques like high-performance liquid chromatography (HPLC) or similar methods to measure eicosanoic acid concentration accurately.

What Does the Result Mean?

Interpretation of results depends on clinical context, such as your symptoms, medical history, and other test results. Abnormal levels may suggest metabolic imbalances or conditions affecting fatty acid processing, but reference ranges vary by lab and may not be widely standardized.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Eicosanoic Acid Level

Frequently asked questions

What could cause abnormal eicosanoic acid levels?
Abnormal levels may be linked to genetic metabolic disorders, certain medications affecting lipid metabolism, or conditions like diabetes or obesity that alter fatty acid profiles. Always discuss results with your healthcare provider.
How often should I get this test?
This test is not routinely recommended for general health screening. Your doctor will determine if it’s needed based on your symptoms, medical history, or specific clinical questions.
Is fasting required for this test?
Fasting may not be required, but your doctor may provide specific instructions based on the clinical reason for testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy