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Eicosanoic Acid in Cerebrospinal Fluid (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of eicosanoic acid, a fatty acid found in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord). It may be checked to help assess certain metabolic or inflammatory conditions.

Quick summary

["Eicosanoic acid in CSF can provide insights into metabolic or inflammatory processes in the central nervous system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53466-9
Short code
Eicosanoylcarn CSF-sCnc
Synonyms
Eicosanoylcarn CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect conditions like metabolic disorders, certain neurological diseases, or abnormalities in fat metabolism within the brain. It could also be part of a broader evaluation for unexplained symptoms such as headaches, seizures, or cognitive changes.

What to Expect Before the Test

No special preparation is typically required for this test. You may have a small needle inserted into your lumbar spine to collect a sample of cerebrospinal fluid. This is usually done in a hospital or clinic setting and may cause mild discomfort but is generally well-tolerated.

What the Results Mean

Eicosanoic acid levels in CSF can vary based on underlying health conditions, diet, and other factors. While specific reference ranges aren’t universally defined for this test, elevated or abnormal levels might suggest metabolic issues, fatty acid disorders, or other neurological concerns that need further evaluation.

Common Conditions Monitored

This test may be used to monitor conditions related to abnormal fat metabolism, such as certain inherited disorders affecting fatty acid breakdown. It can also be part of investigations into inflammatory or metabolic diseases affecting the central nervous system.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Eicosanoic Acid

Frequently asked questions

What does a high or low eicosanoic acid level in CSF typically indicate?
High levels of eicosanoic acid in CSF might suggest metabolic disorders, fatty acid storage diseases, or other conditions affecting fat metabolism within the central nervous system. Low levels, if abnormal, could indicate other metabolic or neurological concerns, but results should always be reviewed by a healthcare professional.
How often is this test repeated if results are abnormal?
If initial results are abnormal, your healthcare provider may repeat the test or order additional tests to better understand the cause. The frequency depends on your specific condition and treatment plan, which will be determined by your doctor.
Is there any dietary or lifestyle change I should make before or after this test?
No specific dietary restrictions are typically required for this test. However, if your healthcare provider suspects a metabolic condition, they may recommend dietary adjustments or further testing to guide treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy