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Serum or plasma concentration of vitamin E (alpha-tocopherol)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin E, a fat-soluble antioxidant found in your blood. Vitamin E helps protect cells from damage caused by free radicals.

Quick summary

["Vitamin E supports cell health and immune function; low levels may indicate nutritional deficiencies or absorption issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31823-8
Short code
EIV Ag Nose Ql
Synonyms
EIV Ag Nose Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a vitamin E test to check for deficiencies, especially if you have symptoms like muscle weakness, nerve problems, or frequent infections. It can also help diagnose conditions like malabsorption disorders (e.g., celiac disease) or liver problems. Rarely, it may be used to monitor vitamin E supplementation.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if your lab uses a specific method. Avoid taking vitamin E supplements 24 hours prior to testing, as they can affect results.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick. The blood sample is then sent to a lab for analysis.

What Do Results Mean?

Results are compared to a reference range, but exact values can vary by lab. Low levels may suggest poor absorption, liver disease, or certain genetic conditions. High levels could indicate over-supplementation or rare metabolic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin E deficiency is rare in healthy individuals but can occur in people with chronic liver disease, cystic fibrosis, or conditions that impair fat absorption. It plays a role in preventing oxidative damage to cells and may support immune function. Monitoring levels helps identify underlying issues that could affect overall health.

Short name

Vitamin E level

Frequently asked questions

What causes vitamin E deficiency?
Deficiency is most commonly linked to malabsorption disorders (e.g., celiac disease, Crohn’s disease) or liver problems. Rarely, genetic disorders or very low-fat diets can also lead to low levels.
What symptoms might indicate low vitamin E?
Symptoms of deficiency may include muscle weakness, nerve damage (tingling, numbness), vision problems, or frequent infections. However, many people with mild deficiencies have no symptoms.
Can vitamin E supplements affect test results?
Yes, taking vitamin E supplements within 24 hours of testing may raise your results. Your doctor or lab may instruct you to avoid supplements to get an accurate measurement.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy