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Leukocyte Elastase, Plasma — Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

Measures the amount of leukocyte elastase, also called neutrophil elastase, in plasma. It may be used as a marker of neutrophil activation and inflammation.

Quick summary

["This blood test measures leukocyte elastase, a marker that can increase when neutrophils are activated during inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33864-0
Short code
Elastase Leukocyte Plas-mCnc
Synonyms
Elastase Leukocyte Plas-mCnc
Category
liver
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 100 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Leukocyte elastase, also called neutrophil elastase, is an enzyme released by activated white blood cells called neutrophils. This test measures its mass concentration in plasma, the liquid portion of blood.

Why might I need this test?

A clinician may order this test to assess neutrophil activity as part of an evaluation of inflammation or certain immune-related conditions. It is usually interpreted together with symptoms, medical history, and other laboratory results.

How is the test performed?

A blood sample is collected, and the plasma is separated and analyzed to determine the amount of leukocyte elastase. The laboratory may use an immunoassay or another validated testing method.

How do I prepare for the test?

Follow the instructions provided by your clinician or laboratory. No special preparation is commonly required for a routine blood draw, although you should tell the laboratory if you have a bleeding disorder or take blood-thinning medicines.

Reference range

Adult: 10-40 U/LN/A

Specimen: plasma

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Leukocyte Elastase

Frequently asked questions

Is leukocyte elastase the same as pancreatic elastase?
No. Leukocyte elastase, also called neutrophil elastase, comes from activated neutrophils. Pancreatic elastase is produced in the pancreas and is a different test.
What does a high leukocyte elastase result mean?
It may suggest increased neutrophil activation and is often associated with an inflammatory or immune-related process. The result is not specific to one condition and must be interpreted with other findings.
Does this test require fasting?
Fasting is not generally required unless your clinician or laboratory specifically instructs you to fast. Confirm the preparation instructions before the blood sample is collected.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy