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Free Pancreatic Elastase, Serum — Catalytic Concentration

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures the activity of free pancreatic elastase, an enzyme produced by the pancreas.

Quick summary

["This test measures pancreatic elastase activity in blood, which may help evaluate pancreatic function or pancreatic disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2220-2
Short code
Elastase Panc Free Ser-cCnc
Synonyms
Elastase Panc Free Ser-cCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
0.5 N/A – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures the activity of free pancreatic elastase. Pancreatic elastase is an enzyme made by the pancreas that helps digest proteins.

Why might I need this test?

The test may be ordered to help evaluate pancreatic function or investigate symptoms such as abdominal pain, indigestion, or changes in bowel habits. It may be used alongside other pancreatic tests because no single result provides a complete picture.

How is the test performed?

A blood sample is collected and sent to a laboratory. The laboratory measures the catalytic activity, or ability to act as an enzyme, of free pancreatic elastase in the serum.

How do I prepare for the test?

Special preparation is usually not required for this serum test. Follow any instructions from your healthcare professional, and tell the laboratory if you are pregnant or have recently received certain treatments that could affect the result.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lower pancreatic elastase activity may be associated with reduced pancreatic function, while higher activity can occur with pancreatic inflammation or injury. Results should be interpreted with symptoms, examination findings, and other laboratory or imaging tests because abnormal values are not specific to one condition.

Short name

Serum Pancreatic Elastase

Frequently asked questions

What does pancreatic elastase measure?
It measures the activity of pancreatic elastase, a digestive enzyme produced by the pancreas. The result reflects enzyme activity rather than simply the amount present.
Is this the same as a fecal pancreatic elastase test?
No. This test uses a blood sample, while fecal pancreatic elastase testing uses a stool sample. Your healthcare professional can clarify which test is appropriate for your situation.
Does an abnormal result diagnose a pancreatic disorder?
Not by itself. The result must be considered with your symptoms, medical history, other tests, and sometimes imaging to determine its clinical meaning.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy