Skip to content

Pancreatic Elastase, Stool — Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

A stool test that measures pancreatic elastase to help assess pancreatic exocrine function, especially when reduced digestive enzyme output is suspected.

Quick summary

["Low pancreatic elastase in stool may indicate that the pancreas is not producing enough digestive enzymes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
25907-7
Short code
Elastase Panc Stl-mCnt
Synonyms
Elastase Panc Stl-mCnt
Category
liver
Sample
stool
Container
Clean container
Units
N/A
Ref low
10
Ref high
40
Critical range
0.5 N/A – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

What is this test?

This test measures pancreatic elastase in stool. It is commonly known as fecal pancreatic elastase-1 and helps evaluate how well the pancreas is producing digestive enzymes.

Why might I need this test?

The test may be ordered for symptoms such as chronic diarrhea, weight loss, oily or foul-smelling stools, bloating, or poor nutrient absorption. It can help evaluate possible pancreatic exocrine insufficiency, including chronic pancreatitis or other pancreatic disorders.

How is the test performed?

A stool sample is collected and sent to a laboratory, where pancreatic elastase is measured using a laboratory assay. Depending on the laboratory, more than one stool sample may be requested to improve the reliability of the result.

How do I prepare for the test?

This test usually does not require fasting. Collect the stool in the container provided and follow the laboratory's instructions for the number of samples, refrigeration, and delivery timing. Do not add disinfectant, bleach, or toilet water to the sample.

Reference range

Adult: 10-40 U/LN/A

Specimen: stool

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Stool pancreatic elastase

Frequently asked questions

Does this test diagnose chronic pancreatitis?
No. It provides evidence about pancreatic digestive enzyme function but usually must be interpreted alongside symptoms, imaging, and other tests.
Is fasting required for a stool pancreatic elastase test?
Usually not. Follow the specific collection kit instructions, as some laboratories request multiple samples or special handling.
What can cause a low pancreatic elastase result?
Low results may occur when the pancreas produces or releases insufficient digestive enzymes, including with chronic pancreatitis, obstruction, or certain inherited conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy