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Pancreatic Elastase, Stool — Qualitative

Published: August 9, 2026Updated: August 17, 2026

A stool test that checks for pancreatic elastase, an enzyme linked to pancreatic function. It may help evaluate suspected pancreatic insufficiency.

Quick summary

["This test can help assess whether the pancreas is producing enough digestive enzymes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
42902-7
Short code
Elastase Panc Stl Ql
Synonyms
Elastase Panc Stl Ql
Category
liver
Sample
stool
Container
Clean container
Units
N/A
Ref low
10
Ref high
40
Critical range
0.5 N/A – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

What is this test?

Pancreatic elastase is an enzyme made by the pancreas and released into the digestive tract. This qualitative stool test detects its presence and may be used to help assess pancreatic function.

Why might I need this test?

Your clinician may order this test if you have symptoms suggesting pancreatic insufficiency, such as persistent diarrhea, oily or foul-smelling stools, unexplained weight loss, or poor nutrient absorption. It may also be used when monitoring conditions that affect the pancreas.

How is the test performed?

A small stool sample is collected and tested in the laboratory for pancreatic elastase. The result is reported as positive or negative rather than as a specific numerical measurement.

How do I prepare for the test?

Follow your clinician's instructions about which stool sample to submit and when to collect it. Tell the laboratory if you are taking medicines that may affect digestion or pancreatic function, and do not stop prescribed medicines without medical advice.

Reference range

Adult: 10-40 U/LN/A

Specimen: stool

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result generally indicates that pancreatic elastase is present in the stool. An unexpected negative result may suggest reduced pancreatic enzyme output or pancreatic insufficiency, but it can also occur with sample problems or certain digestive conditions, so results should be interpreted alongside symptoms and other testing.

Short name

Stool Pancreatic Elastase

Frequently asked questions

What does a positive result mean?
It means pancreatic elastase was detected in the stool sample. This is usually considered consistent with enzyme activity reaching the digestive tract.
What does a negative result mean?
It means pancreatic elastase was not detected. This may occur with pancreatic insufficiency, but the result can also be influenced by the sample or other digestive conditions.
Is this the same as a fecal fat test?
No. A stool pancreatic elastase test looks for a pancreatic digestive enzyme, while a fecal fat test measures fat in the stool to assess absorption.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy