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Serum/plasma mass concentration of erythrocyte membrane-associated protein linked to complement regulation (e.g., decay-accelerating factor)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein found on red blood cell membranes that helps regulate the immune system’s complement pathway.

Quick summary

["This test helps assess how well your immune system’s complement system is functioning."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80195-1
Short code
EME SerPl Cfm-mCnc
Synonyms
EME SerPl Cfm-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects a specific protein on red blood cells that plays a role in preventing excessive activation of the complement system—a series of proteins that help fight infections. Abnormal levels may indicate underlying immune or inflammatory conditions.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of immune dysfunction, such as chronic inflammation, autoimmune diseases, or conditions affecting red blood cells.

Common Conditions Monitored

While less common, this test may be used in research or specialized cases involving rare genetic disorders or immune-related conditions that affect red blood cell membranes.

What to Expect Before the Test

No special preparation is needed. You may have blood drawn from a vein in your arm, similar to other blood tests. If you’re on blood thinners, let your provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

None

Frequently asked questions

How is this test different from standard blood tests?
Unlike typical blood tests (e.g., CBC or electrolytes), this test focuses specifically on a protein found in red blood cell membranes. It’s not routinely part of standard care but may be used in specialized clinical scenarios.
What does a high or low result mean?
Results beyond normal ranges may indicate immune system imbalances or genetic factors affecting red blood cells. Your provider will discuss findings in the context of your overall health.
Can diet or lifestyle affect this test?
Dietary factors or lifestyle choices typically don’t directly influence this specific protein measurement, but they may impact related health conditions (e.g., inflammation). Follow your provider’s advice for general health support.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy