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Albumin to Creatinine Ratio (Fluid)

Published: August 9, 2026Updated: August 16, 2026

This test measures the ratio of albumin (a protein) to creatinine (a waste product) in your urine over 24 hours. It helps assess how much protein leaks into your urine, which can indicate kidney function or damage.

Quick summary

["This ratio helps detect early kidney issues by tracking protein loss in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63393-3
Short code
ENA Jo1 Ab Fld IA-aCnc
Synonyms
ENA Jo1 Ab Fld IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like swelling, frequent urination, or unexplained fatigue. It’s also used in monitoring conditions like kidney disease, diabetes, or high blood pressure.

How the Test Works

You’ll collect all your urine for 24 hours and send it to the lab. The lab measures albumin and creatinine levels in the urine sample to calculate the ratio.

What to Expect Before the Test

No special preparation is needed, but drink plenty of fluids unless instructed otherwise. Avoid certain medications or foods that might affect protein levels (like salt or certain supplements) without consulting your doctor.

Possible Results and Next Steps

A higher ratio may suggest kidney problems or protein loss, while a normal ratio usually indicates healthy kidney function. Your doctor will discuss results with you and may recommend further testing if needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for identifying kidney-related conditions early, such as nephrotic syndrome or diabetic nephropathy. It helps monitor progression of kidney damage and guides treatment decisions.

Short name

Albumin:Creatinine Ratio (24-hour urine)

Frequently asked questions

What does an abnormal result mean?
An abnormal result may indicate kidney issues, such as proteinuria (excess protein in urine), which could be caused by kidney disease, diabetes, or other health conditions. Your doctor will review your full medical history and other test results to determine the next steps.
How often should I get this test?
The frequency depends on your health condition. If you have kidney disease, diabetes, or high blood pressure, your doctor may recommend this test every few months or annually. Follow their guidance for regular monitoring.
Can diet or medications affect this test?
Yes, certain foods (like high-sodium diets), medications (such as NSAIDs or certain blood pressure drugs), or health conditions (like kidney disease) can influence albumin levels in urine. Always inform your doctor about all medications and dietary changes before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy