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Serum Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your serum. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test checks kidney function by measuring waste product levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33571-1
Short code
ENA Jo1 IgG Ser-aCnc
Synonyms
ENA Jo1 IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor kidney health, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used before certain procedures or medications to ensure your kidneys are functioning properly.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader kidney function panel. Drink plenty of water the day before to help dilute urine if it’s a urine-based test (though this test is serum-based).

What Happens During the Test?

A small blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab to measure creatinine levels. The process takes a few minutes and may cause a slight pinch.

What Do Results Mean?

Results help determine if your kidneys are working as expected. Abnormal levels may signal kidney damage or disease, but interpretation depends on your overall health and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function because they reflect how well blood is filtered. High levels may suggest kidney damage, chronic kidney disease, or conditions like diabetes or heart disease. Low levels could indicate dehydration or muscle loss, though this is less common. Regular monitoring is important for those with risk factors like hypertension or diabetes.

Short name

Creatinine

Frequently asked questions

How often should I get this test?
The frequency depends on your health status. Healthy adults may not need routine testing, but people with kidney risk factors (e.g., diabetes, high blood pressure) may need it every few months or annually. Your doctor will guide you based on your medical history.
What causes creatinine levels to change?
Creatinine levels can rise due to kidney problems, dehydration, or muscle breakdown (e.g., from injury or illness). They may also drop if you’re severely dehydrated or have very low muscle mass. Dietary protein intake can affect levels, but creatinine itself doesn’t come from food.
Can I adjust my diet to affect creatinine levels?
While diet doesn’t directly change creatinine levels, managing protein intake may help if you have kidney concerns. High-protein diets can temporarily raise levels, but long-term effects depend on kidney health. Always follow your doctor’s advice.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy