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Serum or plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Bilirubin levels help diagnose and monitor liver and bile duct conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44332-5
Short code
ENA Jo1 IgG Ser Ql
Synonyms
ENA Jo1 IgG Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order a total bilirubin test to check for liver disease, such as hepatitis, cirrhosis, or blockages in the bile ducts. It can also help identify conditions like hemolytic anemia, where red blood cells break down too quickly, or gallstones that may be blocking bile flow.

What does the test involve?

A small blood sample is taken from a vein in your arm. The blood is sent to a lab where it is analyzed to determine the total bilirubin concentration. No special preparation is usually needed, but you may be asked to avoid certain medications or foods for a short time before testing.

What are the results typically used for?

Results help identify abnormal bilirubin levels, which can indicate underlying health issues. High levels may suggest liver problems, while low levels are less common but can sometimes be linked to certain genetic conditions or liver diseases.

What might abnormal results mean?

Elevated bilirubin levels can signal conditions like jaundice (yellowing of the skin and eyes), liver disease, or bile duct obstructions. Low levels are less frequently significant but may warrant further investigation to rule out rare conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance

Short name

Total bilirubin

Frequently asked questions

How long does it take to get results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will discuss the results with you during your follow-up visit.
Can I eat or drink before this test?
You can typically eat and drink normally before this test unless your doctor instructs otherwise. Some tests may require fasting, but this is not the case for total bilirubin.
Is there any risk or discomfort with this test?
The blood draw may cause a slight pinch or discomfort, but it usually goes away quickly. There’s a very small risk of bruising or swelling at the site, but serious complications are rare.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy