Cerebrospinal Fluid (CSF) Protein by Electrophoresis
This test measures the different types of proteins found in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord). It helps identify abnormalities in protein distribution that may indicate conditions like multiple sclerosis, infections, or other neurological disorders.
["This test helps diagnose and monitor conditions affecting brain and spinal fluid protein levels."]
Key facts at a glance
- LOINC
- 63306-5
- Short code
- ENA PCNA Ab CSF Ql IA
- Synonyms
- ENA PCNA Ab CSF Ql IA
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates proteins in your CSF based on size and electrical charge. This process creates bands that represent different protein types, such as albumin, globulins, and other proteins. Each band’s appearance can indicate underlying health issues.
Why Might You Need This Test?
Your doctor may order this test if you have symptoms like headaches, vision problems, numbness, or weakness that suggest conditions like meningitis, multiple sclerosis, or other neurological disorders. It helps assess protein abnormalities in CSF.
How Is the Sample Collected?
A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). A needle is inserted into your lower back to draw fluid into a sterile container. You may feel pressure or mild discomfort, but it’s usually brief.
What Are Common Results?
Results show protein bands that may appear normal or abnormal. For example, elevated globulins could suggest inflammation or immune system activity, while abnormal patterns might point to conditions like Guillain-Barré syndrome or tumors.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test plays a key role in diagnosing neurological disorders by revealing protein imbalances in CSF. For instance, elevated protein levels or specific band patterns can indicate infections, autoimmune diseases, or tumors affecting the central nervous system. Early detection helps guide treatment decisions.
Short name
CSF Protein Electrophoresis
Frequently asked questions
What does an abnormal protein pattern in CSF mean?
How long does it take to get results from this test?
Can lifestyle changes affect CSF protein levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy