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Serum or plasma concentration of angiotensin-converting enzyme (ACE)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of angiotensin-converting enzyme (ACE) in your blood. ACE is an enzyme involved in regulating blood pressure and fluid balance.

Quick summary

["ACE levels can help diagnose or monitor conditions affecting your lungs, heart, or immune system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47074-0
Short code
ENA PCNA Ab Ser Ql IF
Synonyms
ENA PCNA Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order an ACE test to check for conditions like sarcoidosis (a disease causing inflammation in organs), lymphangioleiomyomatosis (LAM, a rare lung disease), or certain types of heart or kidney disease. It may also be used to monitor treatment progress or screen for genetic disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your lab uses a fasting protocol. Avoid smoking or strenuous activity for 30 minutes before testing.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a small pinch, but it typically only takes a few minutes. The blood sample is then sent to a lab for testing.

What the Results Mean

ACE levels can vary widely depending on the condition being tested. Higher or lower than expected levels may signal underlying health issues, but your provider will interpret results in the context of your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

ACE Level

Frequently asked questions

What causes ACE levels to change?
ACE levels can be influenced by medications (like ACE inhibitors, which lower blood pressure), pregnancy, or certain infections. Chronic illnesses, such as kidney disease or heart failure, may also affect ACE levels. Smoking can temporarily lower ACE levels, so it’s best to avoid it before testing.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they have the results.
Can lifestyle changes affect ACE test results?
Yes, lifestyle factors like smoking, diet, or exercise can influence ACE levels. Avoid smoking for at least 30 minutes before testing, and follow any fasting instructions if required. Hydration and stress levels may also play a role, so try to relax before your appointment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy