Cerebrospinal Fluid Protein by Electrophoresis (Qualitative)
This test measures the types and amounts of proteins found in your cerebrospinal fluid (CSF), which surrounds your brain and spinal cord. It helps identify abnormalities in protein distribution that may indicate conditions like multiple sclerosis, infections, or other neurological disorders.
["This test helps diagnose and monitor conditions affecting your brain and spinal cord by examining protein patterns in CSF."]
Key facts at a glance
- LOINC
- 63308-1
- Short code
- ENA PM/SCL Ab CSF Ql IA
- Synonyms
- ENA PM/SCL Ab CSF Ql IA
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you have symptoms like headaches, vision changes, numbness, weakness, or balance issues that suggest a neurological condition. It’s also used to check for infections, tumors, or inflammatory diseases in the central nervous system.
How the Test Works
A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then analyzed using electrophoresis, a method that separates proteins based on size and charge to identify patterns.
Sample Collection and Preparation
You’ll lie on your side with your back bent slightly. A needle is inserted into your lower back to collect CSF. The procedure is quick but may cause mild discomfort. The sample is sent to the lab for analysis without further preparation needed.
What to Expect After the Test
You’ll need to stay in bed for a short time to prevent bleeding or bruising. Mild soreness or a headache may occur, but these usually go away within a few hours or days. Avoid heavy lifting or strenuous activity for 24 hours.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein patterns in CSF can signal conditions such as multiple sclerosis (where proteins like IgG may appear in excess), meningitis (elevated white blood cells and proteins), or tumors (unusual protein bands). This test helps guide treatment decisions and monitor disease progression.
Short name
CSF Protein Electrophoresis (Qual)
Frequently asked questions
What does a normal result mean?
How long does it take to get results?
Can I eat or drink before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy