Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

What This Test Measures

The bromocresol green (BCG) dye test works by measuring how much of the dye binds to proteins in your serum or plasma. When the dye binds, it changes color, which is detected and quantified. This process reflects the concentration of certain proteins, such as albumin, which can be influenced by liver function or overall protein synthesis.

Why It’s Done

Doctors may order this test to check for liver disease, protein malnutrition, or other conditions affecting protein levels in the blood. It can also be part of routine monitoring for patients with known liver issues or those undergoing treatments that may impact protein production.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in the arm. The sample is then processed to separate serum or plasma, which is sent to the lab for testing. The dye binding process is automated and typically requires minimal additional steps beyond standard lab preparation.

Possible Results and Interpretation

Results are reported as a concentration value, though exact reference ranges may vary by lab. Lower than expected values may suggest liver disease, malnutrition, or other conditions affecting protein synthesis. Higher values might indicate dehydration or other factors increasing protein concentration.