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Serum/Plasma Protein Electrophoresis with Bromocresol Green (BCG) Dye Binding

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different protein types in your blood using a dye that binds to specific proteins, helping identify abnormalities in protein levels.

Quick summary

["Assists in diagnosing conditions affecting blood protein balance, such as kidney disease or certain cancers."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63399-0
Short code
ENA RNP Ab CSF IA-aCnc
Synonyms
ENA RNP Ab CSF IA-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses bromocresol green dye to separate and quantify proteins in your blood, including albumin, globulins, and other fractions. This helps assess overall protein composition and identify shifts that may indicate health issues.

Common Uses

This test is often used to diagnose conditions like multiple myeloma, liver disease, kidney problems, or certain autoimmune disorders. It can also help monitor treatment progress for these conditions.

How the Test Works

A small blood sample is drawn and mixed with bromocresol green dye. The proteins in the sample bind to the dye differently, allowing them to separate during electrophoresis. The resulting pattern helps determine protein concentrations.

Preparation Tips

No special preparation is needed, but avoid heavy meals or excessive alcohol before the test. Hydration is generally encouraged unless advised otherwise by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal protein patterns may signal underlying health problems, such as an overproduction of certain proteins (e.g., monoclonal gammopathy in multiple myeloma) or reduced protein levels (e.g., in liver or kidney disease). Early detection can guide treatment decisions.

Short name

BCG Protein Electrophoresis

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if they suspect conditions like multiple myeloma, liver disease, kidney problems, or certain autoimmune disorders. It can also help monitor protein levels during treatment for these conditions.
What does it mean if my results are abnormal?
Abnormal results may indicate an imbalance in protein levels, which could point to conditions like kidney disease, liver disease, or cancers such as multiple myeloma. Your doctor will discuss these findings with you in detail.
Results are typically available within a few days to a week, depending on lab processing times. Your healthcare provider will contact you to review the results and any follow-up steps.
Avoid heavy meals or alcohol before the test. You may experience mild discomfort at the needle site, but this usually resolves quickly. If you have questions about your test, ask your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy