Serum or plasma protein electrophoresis (qualitative or semi-quantitative)
This test measures the types and amounts of proteins in your blood, separated by size and charge. It helps identify abnormalities in protein distribution, which can signal conditions like multiple myeloma, liver disease, or other disorders.
["This test helps doctors check for unusual protein patterns that may indicate hidden health issues."]
Key facts at a glance
- LOINC
- 63540-9
- Short code
- ENA RNP Ab Fld Ql
- Synonyms
- ENA RNP Ab Fld Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if they suspect conditions affecting protein production, such as blood cancers, kidney disease, or liver problems. It’s also used to monitor certain treatments or diagnose symptoms like unexplained weight loss, fatigue, or swelling.
How the Test Works
A small blood sample is taken and placed on a gel. An electric current is applied, causing proteins to move toward the opposite charge. After separation, the proteins are stained and visualized to show distinct bands representing different protein types.
Sample Collection
You’ll have a needle inserted into your arm to draw blood. The process is quick and usually painless. If you’re nervous, let your healthcare provider know—they can use a tourniquet or apply a numbing cream if needed.
What to Expect After
You may feel slight bruising or soreness at the site, but no special care is needed beyond applying ice if needed. Avoid vigorous activity for a few hours to prevent excessive bleeding.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein patterns can reveal hidden health issues, such as high levels of abnormal proteins (e.g., monoclonal gammopathy) linked to diseases like multiple myeloma. Low albumin or altered globulin ratios may indicate liver, kidney, or nutritional problems. This test is critical for early detection and guiding treatment decisions.
Short name
Protein Electrophoresis
Frequently asked questions
What does a protein electrophoresis test measure?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy