Skip to content

Serum or Plasma Protein Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, separated by size and charge, to help identify abnormalities in protein distribution.

Quick summary

["Assesses protein patterns that may signal conditions like multiple myeloma, liver disease, or other protein disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63318-0
Short code
ENA RNP Ab Fld Ql IA
Synonyms
ENA RNP Ab Fld Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins into fractions, including albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal bands or shifts may indicate underlying health concerns.

Why Is This Test Done?

Your healthcare provider may order this test to diagnose or monitor conditions such as multiple myeloma, liver disease, kidney disease, or certain autoimmune disorders.

Sample Collection and Preparation

A blood sample is drawn, and the serum or plasma is analyzed using an electric field to separate proteins. Results are qualitative, meaning they describe patterns rather than specific numeric values.

Common Conditions Evaluated

Abnormal electrophoresis results can signal conditions like monoclonal gammopathy (excess monoclonal proteins), hypoalbuminemia, or increased globulins, which may require further testing or treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Protein electrophoresis is critical for detecting and managing conditions that alter protein composition. For example, a prominent spike in gamma-globulins may suggest multiple myeloma or other plasma cell disorders, while low albumin levels could indicate liver or kidney dysfunction.

Short name

Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test show?
It shows the relative amounts of different protein groups (albumin, globulins) and may reveal unusual bands or patterns that could indicate health issues like protein disorders or organ damage.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times.
Can I eat or drink before this test?
No special diet is required, but inform your provider if you’re on certain medications that might affect protein levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy