Skip to content

Albumin to Total Protein Ratio (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the proportion of albumin protein to total protein in your blood, which helps assess protein balance and kidney function.

Quick summary

["A useful check for protein loss or kidney issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109740-1
Short code
ENA RNP Ab Msmt CSF
Synonyms
ENA RNP Ab Msmt CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Albumin is a key protein produced by your liver that helps maintain fluid balance and supports immune function. Total protein includes albumin plus other proteins like globulins. This ratio can signal problems like kidney disease, malnutrition, or liver conditions.

How It’s Done

A small blood sample is drawn from your arm. The lab analyzes the serum portion to compare albumin levels to total protein levels using standard laboratory methods.

Common Reasons for Testing

Your doctor may order this test if you have symptoms like swelling, unexplained weight loss, fatigue, or if tests suggest kidney or liver issues.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications or conditions that might affect results, such as kidney disease or liver problems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Albumin:Protein Ratio

Frequently asked questions

A low albumin:protein ratio may indicate kidney problems (like nephrotic syndrome), liver disease, or severe malnutrition. A high ratio could suggest dehydration or certain inflammatory conditions. This test is often used alongside other tests to guide treatment decisions.
This test does not provide absolute protein values but helps identify relative imbalances that may need further investigation.
How long will results take?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can I eat or drink before this test?
No fasting is required, but avoid heavy meals or alcohol 24 hours before the test if your doctor specifies it.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy