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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring how well your kidneys remove waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17536-4
Short code
ENA RNP Ab Ser IF-aCnc
Synonyms
ENA RNP Ab Ser IF-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Your Kidneys Matter

Your kidneys filter waste products, including creatinine, from your blood. When kidneys don’t work well, waste can build up, which can harm your body. This test helps doctors see if your kidneys are working properly.

What to Expect Before the Test

You may have this test done by drawing blood from a vein in your arm. No special preparation is usually needed, but you might be asked to stop certain medications or avoid certain foods for a short time, depending on your doctor’s instructions.

What the Results Mean

Higher-than-normal levels may suggest kidney problems, while lower levels could indicate muscle breakdown or other conditions. Your doctor will compare your results with your health history and other tests to understand what’s happening in your body.

Common Causes of Abnormal Results

High creatinine levels can be caused by kidney disease, dehydration, or conditions that increase muscle breakdown. Low levels might be due to muscle loss, liver disease, or certain medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

What triggers a creatinine test?
Your doctor may order this test if you have symptoms like fatigue, swelling, or frequent urination, or if you have a history of kidney problems, diabetes, or high blood pressure.
How often should I get this test?
Frequency depends on your health. People with kidney disease often get it more often than others, while healthy individuals may only need it if they have risk factors like high blood pressure or diabetes.
Can diet affect creatinine levels?
Yes—eating a lot of protein or being dehydrated can temporarily raise levels. Your doctor may suggest dietary changes or hydration tips if needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy