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Serum or Plasma Erythrocyte Antigen Screening (Blood Grouping)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that could react with red blood cells from another person, helping determine your blood type and compatibility for transfusions.

Quick summary

["This test ensures safe blood matching for transfusions and pregnancy care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32715-5
Short code
ENA Scl70 Ab Titr Ser ID
Synonyms
ENA Scl70 Ab Titr Ser ID
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-diffusion
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters in Transfusions

Blood transfusions require precise matching of blood types to prevent harmful reactions. This test identifies your blood group (A, B, AB, O) and Rh factor (positive/negative), which are critical for compatibility with donor blood.

How It Works: Blood Grouping Process

Your blood sample is tested for specific red blood cell antigens (proteins) and antibodies. If antibodies are found, they may react with certain antigens, which helps determine your blood type and potential risks during transfusions.

When You Might Need This Test

You may need this test before a blood transfusion, during pregnancy (especially if you’re Rh-negative), or if you have conditions like hemolytic anemia that affect blood compatibility.

Common Conditions Linked to Blood Type Screening

While this test itself doesn’t diagnose conditions, it’s often used alongside other tests to rule out blood-related risks, such as hemolytic disease of the fetus and newborn (HDFN) in pregnancy or transfusion reactions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is essential for preventing severe complications during blood transfusions or pregnancy, ensuring safe medical procedures by confirming blood compatibility.

Short name

Blood Type Screening

Frequently asked questions

What happens if my blood type screening shows unexpected antibodies?
Unexpected antibodies may require further testing to determine their cause, such as an autoimmune condition or previous blood transfusions. Your healthcare provider will guide you on next steps, possibly including additional blood work or monitoring.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
No special preparation is needed for this test. You may eat and drink normally, but avoid alcohol for 24 hours before your blood draw if possible, as it may affect blood chemistry.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy