Immunoassay for Antibodies to Neisseria meningitidis Serogroup C (Serogroup C Meningococcal Antibody Test)
This test measures the level of antibodies your immune system produces in response to the Neisseria meningitidis serogroup C bacteria. These antibodies help your body fight off infections caused by this type of bacteria.
["Helps assess immune response to meningococcal vaccination or natural exposure."]
Key facts at a glance
- LOINC
- 63406-3
- Short code
- ENA SM Ab CSF IA-aCnc
- Synonyms
- ENA SM Ab CSF IA-aCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you’ve received the meningococcal vaccine (MenC) or if you’ve been exposed to someone with meningococcal disease. It can also be used to monitor immune response in certain clinical situations.
What to Expect Before the Test
No special preparation is needed. A blood sample will be drawn from a vein in your arm, similar to other blood tests. The process usually takes a few minutes.
How the Test Results Are Interpreted
Results are qualitative (present or absent) and indicate whether detectable antibodies are present. High levels suggest a strong immune response, while low or absent levels may indicate insufficient protection.
Common Reasons for Testing
This test is primarily used to evaluate immune response after vaccination or exposure to meningococcal bacteria, though it’s not a routine screening test for all patients.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for determining if a person has developed immunity against meningococcal serogroup C. Elevated antibody levels suggest protection, while low levels may indicate a need for booster vaccination or further medical evaluation, especially in high-risk groups like young adults, travelers to endemic regions, or those with compromised immune systems.
Short name
Meningococcal C Antibody (Serogroup C IgG)
Frequently asked questions
What Does a Positive Test Mean?
What Does a Negative Test Mean?
How Often Should I Get This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy