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Serum or plasma concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes albumin and other proteins like globulins. Proteins are essential for maintaining fluid balance, supporting immune function, and transporting nutrients.

Quick summary

["Your blood protein levels help doctors assess hydration, kidney function, and overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21523-6
Short code
ENA SM IgG Ser Ql
Synonyms
ENA SM IgG Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for conditions like dehydration, kidney disease, liver problems, or certain infections. It can also help monitor long-term health, especially in people with chronic illnesses.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your arm to draw blood. It usually takes a few minutes, and you may feel a brief pinch. Avoid alcohol for 24 hours before the test if instructed.

What the Results Mean

Results are typically reported in grams per deciliter (g/dL). Low protein levels might suggest malnutrition, kidney issues, or liver disease, while very high levels could indicate dehydration or certain blood disorders.

Common Conditions Monitored

This test is often used to monitor conditions like chronic kidney disease, liver cirrhosis, or severe infections. It can also help diagnose or track diseases like multiple myeloma or severe burns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels provide a broad overview of your body’s protein status. Low levels can signal problems with absorption, organ function, or fluid balance, while high levels may indicate dehydration or inflammation. Your provider will interpret results in the context of your symptoms and medical history.

Short name

Total Protein

Frequently asked questions

How long does it take to get my results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they’re ready.
Can I eat or drink before this test?
You can eat and drink normally unless your provider specifies otherwise. Avoid alcohol for 24 hours before the test if recommended.
What if my protein levels are outside the normal range?
If your results are abnormal, your provider may recommend further testing or adjustments to your treatment plan. They’ll discuss next steps based on your specific situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy