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Serum or Plasma Creatinine (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function and detect early kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110757-2
Short code
ENA SM+RNP IgG Msmt Ser
Synonyms
ENA SM+RNP IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. If your kidneys aren’t working well, creatinine builds up in your blood. This test helps doctors determine if your kidneys are functioning properly or if there may be an issue that needs attention.

What to Expect Before the Test

You won’t need to prepare for this test. It’s usually done by drawing blood from a vein in your arm. If you’re taking certain medications that affect kidney function, your doctor may ask you to stop them temporarily or adjust your dosage.

Possible Results and Next Steps

Results are compared to a standard range, though exact values can vary by lab. High levels may suggest kidney problems, while low levels could indicate conditions like dehydration or muscle loss. Your doctor will discuss your results and any follow-up actions needed.

Common Reasons for This Test

Doctors order creatinine tests to monitor kidney health, especially if you have conditions like diabetes, high blood pressure, or a family history of kidney disease. It may also be part of routine check-ups or before certain treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated creatinine levels often indicate reduced kidney function, which can be caused by conditions like chronic kidney disease, kidney stones, or severe dehydration. Low levels may suggest overhydration or conditions affecting muscle mass. Regular monitoring helps manage long-term health and prevent complications.

Short name

Creatinine Level

Frequently asked questions

Will this test affect my diet or medications?
No special diet is needed for this test, but if you’re on medications that affect kidney function, your doctor may advise temporary adjustments. Avoiding excessive protein intake before the test isn’t necessary, as creatinine levels are influenced by muscle mass rather than diet.
How long will I need to wait for my results?
Results are typically available within a few days to a week, depending on your lab. Your doctor will contact you with the final report, so follow up as scheduled.
Can I still exercise or drink alcohol before the test?
Moderate exercise is fine, but avoid heavy physical activity that could cause dehydration. Limit alcohol before the test, as it may temporarily affect kidney function and your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy