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Serum Creatinine (Creatinine Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function.

Quick summary

["A key indicator of how well your kidneys filter blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105556-5
Short code
ENA SS-A 52kD IgG Ser-aCnc
Synonyms
ENA SS-A 52kD IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine levels help doctors evaluate kidney health by measuring how efficiently your kidneys remove waste products from your blood. High levels may signal impaired kidney function, while low levels could indicate dehydration or other conditions.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a larger panel. Wear comfortable clothing for blood draw.

Common Causes of Abnormal Results

Elevated creatinine levels may occur due to kidney disease, dehydration, severe muscle damage, or conditions affecting blood flow to the kidneys. Low levels might suggest dehydration, overhydration, or certain metabolic disorders.

How Results Are Interpreted

Results are compared to a baseline or reference range provided by your healthcare provider. They consider your age, sex, and overall health when interpreting the results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Regular creatinine testing is essential for monitoring kidney function, especially in people with diabetes, hypertension, or a history of kidney issues. It helps detect early signs of kidney damage or disease progression, allowing for timely medical intervention.

Short name

Creatinine

Frequently asked questions

What does a ‘normal’ creatinine level mean for me?
A ‘normal’ result means your kidneys are likely filtering waste products efficiently. However, reference ranges vary by lab and individual factors, so your doctor will discuss what your specific result means for you.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and any kidney-related conditions. Follow their guidance—some people may need it yearly, while others may need it more or less frequently.
Can diet or exercise affect my creatinine levels?
Diet high in protein or muscle-building foods may temporarily raise creatinine levels, but this usually returns to normal after a few days. Exercise generally doesn’t affect creatinine levels unless it causes significant muscle damage.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy