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Serum or plasma substance concentration (unspecified analyte) measured by immunoassay (CLIA)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence or level of a specific substance in your blood, often used to screen for conditions affecting proteins, antibodies, or other biomarkers.

Quick summary

["This test helps identify potential health issues by checking for abnormal levels of a particular substance in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63348-7
Short code
ENA SS-A Ab Fld IA-aCnc
Synonyms
ENA SS-A Ab Fld IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test measures the concentration of a specific substance in your serum or plasma using a highly sensitive immunoassay method. The exact substance being tested may vary depending on clinical need, but it could include proteins, antibodies, or other biomarkers. The test is often used as a screening tool to detect abnormalities that may indicate conditions such as infections, autoimmune diseases, or other health concerns.

Why It Matters in Your Health

Detecting abnormal levels of certain substances early can help doctors diagnose and manage conditions like infections, autoimmune disorders, or metabolic issues. For example, it may help identify markers of inflammation, immune system activity, or protein abnormalities that could signal underlying health problems.

Common Uses and Indications

This test may be ordered to screen for conditions such as autoimmune diseases (e.g., rheumatoid arthritis, lupus), infections (e.g., viral or bacterial), or other metabolic or genetic disorders. It could also be part of a broader diagnostic workup for unexplained symptoms or chronic health concerns.

Sample Collection and Preparation

A blood sample is typically collected from a vein in your arm. The sample is then processed to separate serum or plasma, which is sent to the lab for testing. You may be asked to fast or avoid certain medications before the test, depending on the specific instructions from your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Unspecified protein/antibody screening

Frequently asked questions

How long will it take to get my results?
Results from this test are usually available within 1 to 3 business days, depending on the lab’s processing schedule and your healthcare provider’s workflow. Your doctor will discuss the results with you during your follow-up visit.
What does a high or low result mean?
Results can vary widely depending on the specific analyte being tested. A high or low result may indicate an underlying health condition, but it doesn’t always mean you have a problem. Your doctor will interpret the results in the context of your medical history and symptoms to determine the next steps.
Can I eat or drink before this test?
Most immunoassay tests for blood do not require fasting, but some may have specific instructions. Always follow your healthcare provider’s or lab technician’s instructions for best results. If unsure, ask your doctor or the lab staff before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy