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Serum or plasma concentration of angiotensinogen (measured by immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of angiotensinogen, a protein in your blood that helps regulate blood pressure and fluid balance.

Quick summary

["Angiotensinogen levels can provide insight into your risk for certain heart and blood vessel conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33610-7
Short code
ENA SS-A IgG Ser-aCnc
Synonyms
ENA SS-A IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Angiotensinogen?

Angiotensinogen is a precursor protein produced by the liver. It circulates in the blood and is converted into angiotensin II, a hormone that narrows blood vessels and increases blood pressure. This process is regulated by enzymes like renin. Abnormal levels may indicate underlying health concerns.

Why Might You Need This Test?

Doctors may order this test to evaluate conditions like hypertension, kidney disease, or genetic disorders affecting protein metabolism. It can also help assess risks for conditions such as preeclampsia or certain types of heart disease.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then processed to separate serum or plasma, where the angiotensinogen protein is measured using an immunoassay method. This test typically requires fasting, but requirements vary by lab.

What Do Results Mean?

Results are compared to reference ranges specific to the lab. Elevated levels may suggest conditions like hyperthyroidism or certain liver diseases, while low levels could be linked to conditions like hypopituitarism or genetic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Angiotensinogen level

Frequently asked questions

What factors could affect my results?
Several factors may influence angiotensinogen levels, including genetics, certain medications (like oral contraceptives or thyroid hormones), liver disease, and hormonal imbalances. Recent protein-rich meals or stress can also temporarily affect results.
How often should I get this test?
The frequency depends on your health condition and doctor’s recommendations. Some patients may need this test annually or more often if managing chronic conditions like hypertension or kidney disease.
Can I prepare for this test?
Most labs recommend fasting for 8–12 hours before the test, but always confirm with your healthcare provider. Avoid smoking or excessive alcohol before the draw, as these can impact results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy