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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["This test helps evaluate liver health and protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17586-9
Short code
ENA SS-B Ab Ser Ql IF
Synonyms
ENA SS-B Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Bromocresol green (BCG) is a dye that binds to albumin, a key protein in your blood. When added to your serum or plasma, it binds to albumin and changes color. The test measures how much dye binds, reflecting the amount of albumin present. This can indirectly indicate liver function, as the liver produces albumin, or conditions affecting protein levels.

Why It’s Done

Doctors may order this test to check for liver disease, malnutrition, or other conditions that alter protein levels. It can also help monitor treatments affecting protein synthesis or liver function.

Common Uses

This test is less commonly used today compared to newer methods but may still be performed in specific cases, such as assessing severe liver impairment or protein deficiencies.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Bring your lab results and any medications you’re taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Dye Binding Assay

Frequently asked questions

What does a low BCG dye binding result mean?
A low result may indicate reduced albumin levels, which can happen with liver disease, malnutrition, or kidney failure. Your doctor will review the result alongside other tests to determine the cause.
Is this test painful?
The test involves a small needle inserted into your arm to draw blood. Most people feel only mild discomfort, similar to a quick pinch. You may experience slight bruising or soreness afterward.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy