Serum/Plasma Substance Concentration (Mass) – Big Molecular Weight Substance (e.g., Immunoglobulin, Protein Complex)

What This Test Measures

The test detects the presence and concentration of a high-molecular-weight substance, such as immunoglobulins (antibodies), certain protein complexes, or other large proteins in your serum or plasma. The method used may involve techniques like immunoassay or nephelometry to quantify these substances accurately.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like chronic fatigue, swelling, frequent infections, or unexplained weight changes. It could also be part of an evaluation for autoimmune diseases, infections, or conditions affecting protein metabolism.

Common Conditions Monitored

This test is often used to monitor conditions like multiple myeloma (a cancer of plasma cells), certain immune disorders, or kidney-related protein abnormalities. It may also help assess liver function or detect abnormal protein synthesis in other systemic diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then separated into serum (liquid after clotting) or plasma (liquid after anticoagulant use) for testing. The sample is sent to a lab where it undergoes analysis to measure the target substance’s concentration.