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Anti-endomysium antibody (qualitative) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures whether your blood contains antibodies against endomysium, a protein found in the muscle fibers of your digestive tract. It helps diagnose certain autoimmune conditions affecting digestion.

Quick summary

["This test may help identify celiac disease or related autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14708-2
Short code
Endomysium Ab Titr Ser
Synonyms
Endomysium Ab Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Used For?

Anti-endomysium antibodies are often checked when doctors suspect celiac disease or another autoimmune condition linked to gluten sensitivity. It can also be used to confirm or monitor treatment response in patients with known digestive issues.

How Is the Test Performed?

A small blood sample is drawn from your arm. The serum portion is tested for the presence of these antibodies using an immunoassay method. Results are reported as either positive or negative, not in numeric values.

What Does a Positive Result Mean?

A positive result strongly suggests celiac disease or a related autoimmune condition affecting the small intestine. However, false positives can occur, so further testing (like a biopsy of your small intestine) may be needed to confirm the diagnosis.

What Does a Negative Result Mean?

A negative result means these antibodies were not detected in your blood sample. While this may rule out celiac disease in some cases, it doesn’t completely exclude other autoimmune or digestive disorders. Follow-up testing may still be recommended.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-Endomysium Antibody (Qualitative)

Frequently asked questions

How often should I get this test?
This test is typically ordered as part of an initial evaluation for suspected celiac disease. If you’ve already been diagnosed or are on a gluten-free diet, your doctor may not recommend repeat testing unless symptoms return or new concerns arise.
What are the possible side effects of this test?
The most common side effect is mild discomfort or bruising at the injection site. Rarely, blood tests can cause allergic reactions, but this is uncommon with standard immunoassay methods.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor specifies otherwise. No fasting is required for this qualitative antibody test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy