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Endomysin Antibody (IgG) - Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against endomysin, a protein found in muscle fibers of the small intestine. These antibodies are often linked to certain autoimmune conditions affecting digestion.

Quick summary

["Endomysin antibodies may help diagnose or monitor conditions like celiac disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31366-8
Short code
Endomysium IgA Ser-aCnc
Synonyms
Endomysium IgA Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Endomysin Antibody Testing Used For?

Doctors may order this test to check for signs of celiac disease or other autoimmune gastrointestinal conditions. It helps confirm whether your immune system is attacking the lining of your small intestine, which can interfere with nutrient absorption.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then sent to a lab where it is processed to measure the presence of endomysin antibodies. The test is typically done on serum, the liquid part of blood after clotting.

What Might Influence Results?

Several factors could affect test results, including recent infections, medications (like steroids or immune-suppressing drugs), or other autoimmune conditions. If you are pregnant or have recently had a vaccination, it may also impact results.

What Are Possible Results?

Results are qualitative (positive or negative) rather than numerical. A positive result suggests a higher likelihood of celiac disease or related conditions, but further testing (like a biopsy of the small intestine) is often needed to confirm the diagnosis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Endomysin Antibody

Frequently asked questions

Why is this test important?
This test is important because it helps identify whether your immune system is attacking the lining of your small intestine, which can lead to celiac disease. Early detection can prevent long-term damage and improve digestive health.
What does a positive result mean?
A positive result means your blood contains antibodies against endomysin, which may indicate an autoimmune response in your digestive system. This often prompts further testing, such as an endoscopy with a biopsy, to confirm celiac disease or another condition.
Can this test be done at home?
No, this test requires a blood sample collected by a healthcare professional. It is not a home test and should only be performed under medical supervision.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy