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Myoglobin (Serum) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of myoglobin, a protein in muscles that helps carry oxygen. It can help identify muscle damage or other conditions affecting muscle tissue.

Quick summary

["Myoglobin helps doctors check for muscle injuries or related health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27038-9
Short code
Endomysium IgA Titr Ser IF
Synonyms
Endomysium IgA Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order a myoglobin test to diagnose or monitor conditions like muscle injuries (such as from trauma or overexertion), heart attacks, or certain muscle diseases. It can also help assess how well treatment is working for conditions like rhabdomyolysis (a serious muscle breakdown).

What Does a Myoglobin Test Involve?

A small blood sample is taken from a vein in your arm. The blood is sent to a lab where it is analyzed to measure myoglobin levels. This test is typically done in a clinic or hospital setting with minimal discomfort, though you may feel slight pain or bruising at the injection site.

What Are Common Results?

Results are reported as a concentration of myoglobin in the blood, measured in micrograms per deciliter (µg/dL). Interpretation depends on clinical context, including symptoms and other test results. Elevated levels may suggest muscle damage or other conditions requiring further evaluation.

How Is This Test Different from Other Tests?

Unlike some muscle enzyme tests, myoglobin is not specific to muscle tissue alone—it can also appear in the blood after heart attacks or other conditions affecting blood vessels. Doctors use it alongside other tests (like troponin) to get a clearer picture of potential issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Myoglobin Level

Frequently asked questions

What Are Possible Causes of Abnormal Results?
Elevated myoglobin levels can occur due to muscle injuries (e.g., strains, fractures), severe exercise, or conditions like rhabdomyolysis. Very high levels may signal kidney problems, as myoglobin can damage kidney tissue if not filtered properly. Always discuss results with your healthcare provider.
What If My Results Are Low?
Low myoglobin levels are less common but may occur in certain genetic muscle disorders or during chronic muscle inactivity. Your doctor will consider your overall health and symptoms to interpret these results.
How Often Should I Get This Test?
The frequency depends on your health condition and treatment plan. If you have a known muscle disorder, heart condition, or are recovering from trauma, your doctor may recommend regular monitoring. Follow-up tests are usually scheduled based on symptoms and lab results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy