Skip to content

Myoglobin, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of myoglobin, a protein in muscles that helps carry oxygen. It can help identify muscle damage or injury.

Quick summary

["Myoglobin levels may rise after muscle injury and can signal serious conditions like heart attacks or severe muscle trauma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110846-3
Short code
Endomysium IgG Msmt Ser
Synonyms
Endomysium IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for muscle damage, such as from exercise, injury, or conditions like rhabdomyolysis. It can also be used alongside other tests to help diagnose conditions affecting the heart or kidneys, such as a heart attack or kidney failure.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm to collect a blood sample. Tell your doctor about any recent muscle injury, illness, or medications you’re taking, as these can affect results.

What Happens During the Test?

A healthcare provider will clean your arm and insert a needle to draw blood. The process usually takes a few minutes. You may feel a slight pinch, but it’s quick and not painful.

What Are Possible Results?

Results are interpreted by your doctor based on your symptoms, medical history, and other tests. Elevated levels may indicate muscle damage, but they can also be influenced by other factors like dehydration or certain medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Myoglobin plays a key role in muscle function, and its release into the bloodstream after injury can signal severe muscle breakdown. High levels may prompt further testing for conditions like rhabdomyolysis (a dangerous muscle breakdown), kidney issues, or heart problems. Your doctor will use these results alongside other information to guide care.

Short name

Myoglobin Level

Frequently asked questions

What does a high myoglobin level mean?
A high level may suggest muscle damage from injury, illness, or overexertion. It can also indicate conditions like rhabdomyolysis, which requires medical attention to prevent kidney damage. Always discuss results with your doctor.
Can diet or medications affect myoglobin levels?
Certain medications, such as statins (for cholesterol) or some muscle relaxants, may influence myoglobin levels. Heavy exercise, dehydration, or recent muscle trauma can also raise levels. Your doctor will consider these factors when reviewing your results.
How soon will I get my test results?
Results are typically available within a few days, depending on your lab. Your doctor will explain what they mean and how they fit into your overall health plan.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy