Endomysial Antibody (IgG) - Serology
This test measures the presence of antibodies against endomysium, a protein found in the muscles of the small intestine. It is commonly used to help diagnose celiac disease, an autoimmune condition where the immune system attacks the lining of the small intestine.
["This test helps identify celiac disease by detecting specific antibodies linked to intestinal damage."]
Key facts at a glance
- LOINC
- 45136-9
- Short code
- Endomysium IgG Ser-aCnc
- Synonyms
- Endomysium IgG Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may recommend this test if you have symptoms like persistent diarrhea, stomach pain, weight loss, or fatigue, especially if you’ve been exposed to gluten or have a family history of celiac disease. It may also be used as part of a screening or confirmation process for suspected celiac disease.
What Does a Positive Result Mean?
A positive result strongly suggests celiac disease, as it indicates the presence of antibodies that attack the small intestine’s lining. However, false positives can occur, so further testing (like a biopsy of the intestine) may be needed to confirm the diagnosis.
What Does a Negative Result Mean?
A negative result means the test did not detect these specific antibodies, which could mean celiac disease is not present. However, it’s important to note that some people with celiac disease may not test positive initially, so follow-up testing or other diagnostic methods may still be required.
What to Expect During the Test
This test involves drawing blood from a vein in your arm. The blood sample is sent to a lab for analysis. It typically takes a few days to receive results, depending on lab processing times.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgG Endomysial Antibody
Frequently asked questions
What are the possible side effects or risks of this test?
How often should I get this test if I have celiac disease?
Can I eat gluten before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy