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Entamoeba histolytica stool antigen detection by nucleic acid probe

Published: August 9, 2026Updated: August 17, 2026

This test checks for the presence of genetic material from *Entamoeba histolytica*, a parasite that can cause intestinal infections.

Quick summary

["A simple stool test to detect a parasite linked to diarrhea and abdominal pain."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
103712-6
Short code
Entamoeba hart DNA Stl Ql NAA+probe
Synonyms
Entamoeba hart DNA Stl Ql NAA+probe
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
84484
SNOMED
302774002
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you’ve had symptoms like persistent diarrhea, abdominal cramps, or blood in your stool, especially after traveling to areas with higher parasite risk. It’s also used to confirm a diagnosis if other tests were inconclusive or if you’ve had recurrent infections.

How the Test Works

A small sample of your stool is collected and analyzed using a specialized probe that targets the parasite’s DNA. This method is highly sensitive and can detect even small amounts of the parasite’s genetic material.

Sample Collection and Preparation

You’ll need to provide a fresh stool sample (collected in a sterile container) on the day of testing. Avoid using commercial collection kits unless instructed by your healthcare provider, as some may interfere with the test’s accuracy.

What to Expect After Testing

Results are typically ready within 24–48 hours. If the test is positive, it confirms the presence of *Entamoeba histolytica* and guides treatment. A negative result means the parasite wasn’t detected in this sample, but it doesn’t rule out infection entirely—retesting may be needed if symptoms persist.

Reference range

Adult: 10-40 U/LN/A

Specimen: stool

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Entamoeba histolytica stool probe

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of *Entamoeba histolytica* DNA in your stool, which may cause amoebiasis—a condition that can lead to severe intestinal inflammation, ulcers, or even liver abscesses. Treatment with antiparasitic medications is usually recommended to clear the infection.
What does a negative result mean?
A negative result means the parasite wasn’t detected in this sample, but it doesn’t guarantee you’re completely free of infection. If you continue to have symptoms, your doctor may order additional tests or retesting to confirm or rule out other causes.
How often should I get retested?
If you’ve had symptoms despite a negative result, retesting may be advised, especially if you’ve traveled to high-risk areas or have a history of recurrent infections. Follow your doctor’s guidance for follow-up testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy