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Enterobacterales Carbapenem Resistance, OXA-48 Carbapenemase — Anaerobic Culture

Published: August 9, 2026Updated: August 16, 2026

A culture-based test that detects Enterobacterales with carbapenem resistance and evaluates for the OXA-48 carbapenemase mechanism.

Quick summary

["A positive result indicates a carbapenem-resistant Enterobacterales isolate with OXA-48 detected."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100902-6
Short code
Enterobac.carb res OXA-48 Anal Cult
Synonyms
Enterobac.carb res OXA-48 Anal Cult
Category
tumor-marker
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for Enterobacterales, a family of bacteria that can include important causes of infection. It also checks for carbapenem resistance and the OXA-48 carbapenemase enzyme, which can make these bacteria difficult to treat with some antibiotics.

Why might I need this test?

Your clinician may order this test to investigate a possible bacterial infection, guide antibiotic treatment, or determine whether resistant bacteria are present. It may also be used for infection-control or public-health purposes.

How is the test performed?

A laboratory specimen is cultured under the specified conditions to look for bacterial growth. If Enterobacterales are recovered, the laboratory evaluates their resistance to carbapenem antibiotics and tests for the OXA-48 resistance mechanism.

How do I prepare for the test?

Follow the specimen-collection instructions provided by your healthcare team. The required specimen and preparation depend on the infection being evaluated. Do not stop prescribed antibiotics unless your clinician instructs you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result may indicate infection or colonization by carbapenem-resistant Enterobacterales, which can limit treatment choices. Detection of OXA-48 identifies a specific carbapenemase mechanism associated with reduced susceptibility to several carbapenem antibiotics. A positive culture does not by itself show that the bacteria are causing the symptoms, so results must be interpreted with the specimen type and clinical situation.

Short name

CRE/OXA-48 culture

Frequently asked questions

What does OXA-48 mean?
OXA-48 is an enzyme, called a carbapenemase, produced by some resistant bacteria. It can reduce the effectiveness of carbapenem antibiotics.
Does a positive result mean I have an infection?
Not necessarily. Resistant bacteria may be present in a specimen without causing an active infection, so the result is interpreted together with symptoms and other laboratory findings.
Are the results available immediately?
No. Culture and resistance testing usually require time for bacteria to grow and be identified. The laboratory will provide the result when testing is complete.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy