Genotypic detection of *Enterobacterales* resistance-associated probe (e.g., carbapenemase or extended-spectrum beta-lactamase genes)
This test checks for specific genes in bacteria from your sample that may make them resistant to certain antibiotics, like carbapenems or extended-spectrum penicillins.
["It helps doctors determine if a bacterial infection could be harder to treat with standard antibiotics."]
Key facts at a glance
- LOINC
- 96306-6
- Short code
- Enterobacterales DNA Bld Pos NAA+n-prb
- Synonyms
- Enterobacterales DNA Bld Pos NAA+n-prb
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- non-probe-amp-tar
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have a suspected bacterial infection caused by *Enterobacterales* (a group of bacteria including *E. coli*, *Klebsiella*, or *Pseudomonas*) and suspect antibiotic resistance. It’s particularly useful when infections don’t respond to standard treatments or in cases requiring specialized care.
What the Test Measures
The test detects the presence of genetic material (DNA) linked to antibiotic resistance mechanisms, such as carbapenemases or extended-spectrum beta-lactamases (ESBLs). These genes can make bacteria resistant to a wide range of antibiotics, including last-resort drugs.
Sample Collection and Processing
The test uses a sample of bacteria collected from your body, such as blood, urine, or other clinical specimens. The DNA from these bacteria is analyzed to identify resistance genes, often through advanced molecular techniques like polymerase chain reaction (PCR).
What the Results Mean
If the test finds resistance genes, it suggests that the bacteria may not respond to certain antibiotics. This information helps guide treatment choices to ensure effective therapy. Results are qualitative (positive or negative) and not tied to specific numeric ranges.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for managing infections where antibiotic resistance is a concern. Identifying resistant genes allows healthcare providers to select more targeted treatments, reducing the risk of treatment failure and the spread of resistant bacteria. It’s especially important in hospitals and healthcare settings where infections can spread quickly.
Short name
Enterobacterales Resistance Probe (Genetic Test)
Frequently asked questions
What does a positive result mean?
How long does it take to get results?
Can this test be used for all types of infections?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy