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Celiac Disease Marker (Anti-Tissue Transglutaminase IgA) Antibody, Stool Probe

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your stool that may indicate celiac disease, a condition where the body’s immune system reacts to gluten, a protein found in wheat, barley, and rye.

Quick summary

["Helps detect celiac disease early with a simple stool sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5001-3
Short code
Enterococ rRNA Spec Ql Probe
Synonyms
Enterococ rRNA Spec Ql Probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Celiac disease can cause digestive issues like chronic diarrhea, bloating, or weight loss, but many people also experience fatigue, anemia, or other symptoms that may not be obvious. This test checks for antibodies that signal an immune response to gluten, even if you haven’t had symptoms yet.

How It Works

Instead of drawing blood, this test uses a special probe inserted into your rectum to collect a small sample of stool. The sample is then tested for specific antibodies linked to celiac disease.

What to Expect Before the Test

No special preparation is needed, but you may feel mild discomfort during the probe insertion. If you’re pregnant, have a history of bleeding disorders, or have a rectal condition, let your doctor know before the test.

What the Results Mean

Positive results suggest a high likelihood of celiac disease, but further testing (like a blood test or biopsy) may be needed to confirm. Negative results mean the antibodies weren’t detected in this sample, but celiac disease can sometimes be missed with a single test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-TTG IgA Stool Probe

Frequently asked questions

If you have symptoms like unexplained weight loss, frequent diarrhea, or fatigue, or if you have a family history of celiac disease, this test may be recommended. Early diagnosis helps manage symptoms and prevents long-term health issues like nutrient deficiencies or damage to the small intestine.
This test is not a definitive diagnosis but can help guide further evaluation. If results are positive, your doctor may order additional tests, such as a blood test for other antibodies or an endoscopy with a biopsy.
How often should I get this test?
If you have celiac disease, your doctor may recommend regular testing to monitor your response to gluten-free diets. If you’re asymptomatic, this test may not be routinely recommended unless you have risk factors or symptoms.
Can I eat normally before this test?
No dietary restrictions are needed for this test, but if you’re being tested for celiac disease, your doctor may advise you to avoid gluten-containing foods for other diagnostic tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy